DEFINING THE ALTERED GLYCOPROTEOMIC SPACE OF THE EARLY SECRETORY PATHWAY BY CLASS I MANNOSIDASE PHARMACOLOGICAL INHIBITION

Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition

N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.This is usually accomplished by a complex system of mannosidases in which those from class I have an outstanding role, commonly involved in the early p

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Analysis Methods for Human Factors in Chemical Plant Accidents

It is important to analyze the cause of an accident so as to prevent further incidents of a similar kind.Variation Tree Analysis (VTA) and Why-Why analysis are accident investigation methods to analyze an accident due to human factors in Mitsubishi Chemical Corporation.VTA is the method to employ time series analysis of the circumstances at the tim

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